World’s Smallest Tape Recorder Is Built From Microbes
Using CRISPR-Cas9, researchers at Columbia University Medical Center have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from disease diagnosis to environmental monitoring.
CRISPR Has Sparked a Research Revolution
CRISPR is allowing scientists to make great strides in many fields in the relatively short time it's been in use. Advances have been made in medicine, nutrition, biology, and more.
What Is CRISPR? Genome editing explained
CRISPR technology is a simple yet powerful tool for editing genomes. It allows researchers to easily alter DNA sequences and modify gene function. Its many potential applications include correcting genetic defects, treating and preventing the spread of diseases and improving crops. However, its promise also raises ethical concerns.
In popular usage, "CRISPR" (pronounced "crisper") is shorthand for "CRISPR-Cas9." CRISPRs are specialized stretches of DNA. The protein Cas9 (or "CRISPR-associated") is an enzyme that acts like a pair of molecular scissors, capable of cutting strands of DNA.
CRISPR, microbes and more are joining the war against crop killers
Agricultural scientists look beyond synthetic chemistry to battle pesticide resistance.
Modifying Fat Content in Soybean Oil with the Molecular Scissors Cpf1
A team from the Center for Genome Engineering, within the Institute for Basic Research (IBS), succeeded in editing two genes that contribute to the fat contents of soybean oil using the new CRISPR-Cpf1 technology: an alternative of the more widely used gene editing tool CRISPR-Cas9.
Broad Institute prevails in heated dispute over CRISPR patents
The US patent office ruled on Wednesday that hotly disputed patents on the revolutionary genome-editing technology CRISPR-Cas9 belong to the Broad Institute of Harvard and MIT, dealing a blow to the University of California in its efforts to overturn those patents.
National Academy of Sciences Human Genome Editing Report
Clinical trials for genome editing of the human germline – adding, removing, or replacing DNA base pairs in gametes or early embryos – could be permitted in the future, but only for serious conditions under stringent oversight, says a new report from the National Academy of Sciences and the National Academy of Medicine. The report outlines several criteria that should be met before allowing germline editing clinical trials to go forward.
Tuberculosis-resistant cows modified with CRISPR
China has used CRISPR/Cas9 to modify cows to be resistant to tuberculosis.
Two Infants Treated with Universal Immune Cells Have Their Cancer Vanish
"Universal immune cells" used to treat infant cancer show the potential of gene editing.
What is CRISPR-Cas9?
CRISPR-Cas9 is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.
Genetic changes in tomatoes may help crops produce early and often
Home gardeners in the U.S. and Europe can thank early tomato growers, who selected plants that ignore seasonal changes in day length, for enabling their backyard bounty. Researchers in the lab of Associate Professor Zachary Lippman at CSHL, compared the genomes of early- and late-flowering wild tomato to unpack the tomato genome.
What exactly is genetically modified food?
You’ve probably seen and heard a lot about genetically modified food in recent months: on the news, among friends, even as a label on the food you eat. But for all the information and opinions out there, there’s still very little explanation about what exactly genetically modified organisms are. To get a good answer, it’s helpful to talk with someone who actually makes them.
Matthew Willmann is director of the College of Agriculture and Life Sciences Plant Transformation Facility at Cornell University. He is someone who makes genetically engineered plants. Not for food and not for commercial purposes—Willmann currently uses biotechnology to modify crops for research only.
Biodiversity and Food Security by Susan McCouch
In this video seminar, Susan McCouch , Rice Genetics Lab, Department of Plant Breeding & Genetics at Cornell University, explains how genomics can help ups better understand rice.
CRISPR 101: A crash course on the revolutionary gene editing tool that’s changing the world
For something that’s been called “a household name for molecular biologists,” many of you have probably never heard of CRISPR, and don’t know why you should be excited (or, possibly, terrified). It’s all about advanced gene therapy and splicing – and it’s bringing sci-fi ideas straight into reality. Here’s a quick FAQ on the science behind CRISPR and why the world is paying such close attention.
A crisp intro to CRISPR, the gene-editing tool shaking up science
How can one technology potentially do so many, and such world-altering, things? This video explain what CRISPR actually is, how exactly it works, and why so many scientists believe it's such a promising tool.
A Visual Guide to Genetic Modification
An infographic from Scientific American that compares CRISPR technology to other GM methods used in crops